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In
order to find in Malian pharmacopeia plants with antibacterial and
analgesic properties, different remedies including Hibiscus
sabdariffa calyces12 have been
tested and their plants used in traditional Malian medicine have been
tested for their antibacterial activity on the germs responsible for
the urinary infections and the cystitis, but also for their analgise
activity. The 2 main formulations (SEH and SET) exhibited interesting results in
terms of antibacterial activity, with 100 μg of aqueous extract.
In the same conditions, Escherishia coli strains were resistant to
ampicilin at 10 μg. 12 Moreover, the study gave data
suggesting that the use of aqueous extracts of these 2 recipes was
indicated to fight against the pain associated to urinary tract
infections during the micturition. Effectively, Hibiscus sabdariffa
exhibits at least similar biochemical composition as Cranberry and
consequently similar physiological effects on urinary tract. Moreover,
in addition of the similar biochemical composition of Hibiscus
sabdariffa and Cranberry, several in vitro studies, proved the various
pharmacological, antibacterial and analgesic activities of the
traditional herbal teas and botanical extracts of Hibiscus sabdariffa,
notably against Escherishia coli. These conclusions allow to support
and to objectivise the traditional therapeutic indications of this
plant.29
Hibiscus sabdariffa is an acidic, anti-bacterial herb that acidifies and deodorizes the urine and protects against urinary infections and the formation of stones thanks to its high levels in organic acids. Protocatechuic acid was isolated from Hibiscus sabdariffa calyces and also demonstrated to have antibacterial action.35,36,3725,26,27 Muangman et al. found that Roselle juice increased the acidity of the urine in renal stone patients as a result of two fatty acids in it, namely palmitic acid and stearic acid. 38,39 In 2005, Lin et Al., investigated for the first time more precisely the in vitro inhibitory effect of Roselle calyx and protocatechuic acid, on the growth of methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii. The results of the study demonstrated that Roselle calyx possessed antimicrobial activity. The study also confirmed that protocatechuic acid, based on its marked antibacterial activity, contributed to the observed antibacterial effect of Roselle calyx.
Hibiscus sabdariffa calyces contain high PACs levels Although traditionally, it was first thought that it was the acidic nature of this herb that prevents bacteria from flourishing (bacteriostatic effect) - it is now established that a bacterial antiadhesion mechanism is responsible and it is generally accepted that urinary acidification is not the major factor responsible for Hibiscus effect on UTIs.25 Several compounds that exhibit potent bacterial antiadhesion activity have been isolated from hibiscus : it is hypothesized that anthocyanins and proanthocyanidins (PACs) contained in Hibiscus sabdariffa calyces act by preventing the E. coli bacteria that causes infection from adhering to the uroepithelium cell, multiplying and colonization of the urinary tract.4,40,41,42
High amounts of flavonoids have been attributed to Hibiscus sabdariffa calyces23 In regards of all these data, it is not surprising that one of the major health benefits traditionally attributed to the ingestion of Bissap (Hibiscus sabdariffa juice) is the maintenance of urinary tract health : Treatment and prevention of urinary infections as well as kidneys disorders. Studies have also proved that it is effective in treating bladder infections.
References
Hibiscus sabdariffa is an acidic, anti-bacterial herb that acidifies and deodorizes the urine and protects against urinary infections and the formation of stones thanks to its high levels in organic acids. Protocatechuic acid was isolated from Hibiscus sabdariffa calyces and also demonstrated to have antibacterial action.35,36,3725,26,27 Muangman et al. found that Roselle juice increased the acidity of the urine in renal stone patients as a result of two fatty acids in it, namely palmitic acid and stearic acid. 38,39 In 2005, Lin et Al., investigated for the first time more precisely the in vitro inhibitory effect of Roselle calyx and protocatechuic acid, on the growth of methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii. The results of the study demonstrated that Roselle calyx possessed antimicrobial activity. The study also confirmed that protocatechuic acid, based on its marked antibacterial activity, contributed to the observed antibacterial effect of Roselle calyx.
Hibiscus sabdariffa calyces contain high PACs levels Although traditionally, it was first thought that it was the acidic nature of this herb that prevents bacteria from flourishing (bacteriostatic effect) - it is now established that a bacterial antiadhesion mechanism is responsible and it is generally accepted that urinary acidification is not the major factor responsible for Hibiscus effect on UTIs.25 Several compounds that exhibit potent bacterial antiadhesion activity have been isolated from hibiscus : it is hypothesized that anthocyanins and proanthocyanidins (PACs) contained in Hibiscus sabdariffa calyces act by preventing the E. coli bacteria that causes infection from adhering to the uroepithelium cell, multiplying and colonization of the urinary tract.4,40,41,42
High amounts of flavonoids have been attributed to Hibiscus sabdariffa calyces23 In regards of all these data, it is not surprising that one of the major health benefits traditionally attributed to the ingestion of Bissap (Hibiscus sabdariffa juice) is the maintenance of urinary tract health : Treatment and prevention of urinary infections as well as kidneys disorders. Studies have also proved that it is effective in treating bladder infections.
References
