Harpagoside, and nothing else !
The traditional use of Devil’s claw in African tribes is an herbal tea of the powder form of the dry root.
Recently, extensive investigations into the biological activity in general and the potential
pharmacological activity in particular, have revealed that iridoids, especially harpagoside, were
shown to exert anti-inflammatory effects similar to NSAIDs, by interacting with Arachidonic
Acid metabolism pathways:
• Action on eicosanoids synthesis
• Action on cyclo-oxygenase, lipoxygenase and NO synthetase
• Action on TNFa liberation
• Action on Cys-LT synthetis
• Action on enzymes responsible for collagen degradation.
Botanical Data
- Harpagophytum procumbens DC.
- Synonym : Uncaria procumbens
- Français : Harpagophyton, griffe du diable , racine de Windhoek
- Deutch: Teufelskrallenwurzel, afrikanische Teufelskralle, Trampelklette
- English : Devil’s claw, gapple plant, wood spider
- Other : Harpagophyti radix
- IridoForce™ is the trademark of Burgundy Botanical Extracts, manufactured under pat-ented process.
- It brings up to 20% harpagoside [HPLC - Pharmacopia, ie 40-50% by UV method].
- IridoForce™ is classified as non-toxic (hazard Category 5).